It's strange how the miracle potion seems to work so perfectly for Chizuru yet all of Shinsengumi's seem to be failures. If we believe Sannan, Chizuru's old man was developing it further. If it was already perfect for Chizuru, what's there to develop? Or did Chizuru receive a dose of the original Western stock that her old man couldn't then manage to replicate?

In any case too bad for Sannan. But I suppose it was worth the risk, seeing how his days as a swordman were over and he couldn't cope with the fact. He chose his second somewhat poorly or cowardly, though, if he really expected somebody like Chizuru to kill him should anything go wrong...

Other than that, the new dude has quite a forked tongue.